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RAD51 monoclonal antibody, clone 13E4

  • Catalog # : MAB12627
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human RAD51.
  • Immunogen:
  • Recombinant protein corresponding to human RAD51.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with RAD51 monoclonal antibody, clone 13E4 (Cat # MAB12627) at 5 ug/mL working concentration.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 5888
  • Gene Name:
  • RAD51
  • Gene Alias:
  • BRCC5,HRAD51,HsRad51,HsT16930,RAD51A,RECA
  • Gene Description:
  • RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
  • Gene Summary:
  • The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • BRCA1/BRCA2-containing complex, subunit 5,DNA repair protein RAD51 homolog 1,RAD51 homolog protein,RAD51, S.cerevisiae, homolog of, A,RecA, E. coli, homolog of,RecA-like protein,recombination protein A
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