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Last updated: 2017/7/23

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IGF1R monoclonal antibody, clone JBW902

  • Catalog # : MAB12559
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human IGF1R
  • Immunogen:
  • Recombinant GST fusion protein corresponding to amino acids 1264-1367 of human IGF1R.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    Immunoprecipitation
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.1 M Tris-glycine, 0.15 M NaCl, pH 7.4 (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skeletal muscle with IGF1R monoclonal antibody, clone JBW902 (Cat # MAB12559) at 5 ug/mL working concentration.
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3480
  • Gene Name:
  • IGF1R
  • Gene Alias:
  • CD221,IGFIR,JTK13,MGC142170,MGC142172,MGC18216
  • Gene Description:
  • insulin-like growth factor 1 receptor
  • Gene Summary:
  • This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
  • Other Designations:
  • soluble IGF1R variant 1,soluble IGF1R variant 2
  • Related Disease
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