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CXCR4 monoclonal antibody, clone 12G5

  • Catalog # : MAB12537
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human CXCR4.
  • Immunogen:
  • cP-MAC-infected Sup-T1 cells
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry
    Immunohistochemistry (Frozen sections)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain, cortex with CXCR4 monoclonal antibody, clone 12G5 (Cat # MAB12537) at 10 ug/mL working concentration.
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of human peripheral blood lymphocytes with CXCR4 monoclonal antibody, clone 12G5 (Cat # MAB12537) followed by biotin-conjugated anti-mouse IgG secondary antibody and PE-conjugated streptavidin.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 7852
  • Gene Name:
  • CXCR4
  • Gene Alias:
  • Gene Description:
  • chemokine (C-X-C motif) receptor 4
  • Gene Summary:
  • This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • C-X-C chemokine receptor type 4,CD184 antigen,chemokine (C-X-C motif), receptor 4 (fusin),chemokine receptor 4,fusin,leukocyte-derived seven-transmembrane-domain receptor,lipopolysaccharide-associated protein 3,neuropeptide Y receptor Y3,seven transmembra
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