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RBBP4 monoclonal antibody, clone 11G10

  • Catalog # : MAB12526
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human RBBP4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-425 of human RBBP4.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Immunofluorescence
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    Immunoprecipitation
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with RBBP4 monoclonal antibody, clone 11G10 (Cat # MAB12526) at 5 ug/mL working concentration.
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 5928
  • Gene Name:
  • RBBP4
  • Gene Alias:
  • NURF55,RBAP48
  • Gene Description:
  • retinoblastoma binding protein 4
  • Gene Summary:
  • This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • MSI1 protein homolog,OTTHUMP00000009691,chromatin assembly factor/CAF-1 p48 subunit,retinoblastoma-binding protein 4,retinoblastoma-binding protein p48
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