TIMP2 monoclonal antibody, clone F27P3A4
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of TIMP2 recombinant protein with TIMP2 monoclonal antibody, clone F27P3A4 (Cat # MAB12521).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast with TIMP2 monoclonal antibody, clone F27P3A4 (Cat # MAB12521) at 10 ug/mL working concentration.
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Specification
Product Description
Mouse monoclonal antibody raised against human TIMP2.
Immunogen
A synthetic peptide corresponding to human TIMP2.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG2a
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 - 15 ug/mL)
Western Blot (1 - 2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of TIMP2 recombinant protein with TIMP2 monoclonal antibody, clone F27P3A4 (Cat # MAB12521).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast with TIMP2 monoclonal antibody, clone F27P3A4 (Cat # MAB12521) at 10 ug/mL working concentration.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TIMP2
Entrez GeneID
7077Gene Name
TIMP2
Gene Alias
CSC-21K
Gene Description
TIMP metallopeptidase inhibitor 2
Omim ID
188825Gene Ontology
HyperlinkGene Summary
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq
Other Designations
tissue inhibitor of metalloproteinase 2|tissue inhibitor of metalloproteinases 2
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Interactome
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Disease
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