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IAPP monoclonal antibody, clone R10/99

  • Catalog # : MAB12508
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human IAPP.
  • Immunogen:
  • A synthetic peptide corresponding to human IAPP.
  • Sequence:
  • ATQRLANFLV
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunofluorescence
    Immunohistochemistry (Frozen sections)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas, islet of Langerhans with IAPP monoclonal antibody, clone R10/99 (Cat # MAB12508).
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 3375
  • Gene Name:
  • IAPP
  • Gene Alias:
  • AMYLIN,DAP,IAP
  • Gene Description:
  • islet amyloid polypeptide
  • Gene Summary:
  • Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq
  • Other Designations:
  • Islet amyloid polypeptide (diabetes-associated peptide; amylin)
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