Mouse monoclonal antibody raised against human IAPP.
A synthetic peptide corresponding to human IAPP.
Immunofluorescence Immunohistochemistry (Frozen sections) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
In tissue culture supernatant (0.09% sodium azide).
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq