SERPINA1 monoclonal antibody, clone 11G2
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human SERPINA1.
Immunogen
Recombinant protein corresponding to full length human SERPINA1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Immunoprecipitation
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.3 (1% BSA, 50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293T cells were transfected with the pCMV6-ENTRY control, Lane 2: HEK293T cells were transfected with pCMV6-ENTRY SERPINA1 cDNA for 48 hrs using SERPINA1 monoclonal antibody, clone 11G2 (Cat # MAB12494) at 1:1000-1:2000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver tissue with SERPINA1 monoclonal antibody, clone 11G2 (Cat # MAB12494) under 10 ug/mL working concentration.Immunoprecipitation
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Gene Info — SERPINA1
Entrez GeneID
5265Protein Accession#
P01009Gene Name
SERPINA1
Gene Alias
A1A, A1AT, AAT, MGC23330, MGC9222, PI, PI1, PRO2275
Gene Description
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin|serine (or cysteine) proteinase inhibitor, clade A, member 1|serine proteinase inhibitor, clade A, member 1
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Interactome
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Pathway
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Disease
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