Western blot analysis of Lane 1: HEK293T cells were transfected with the pCMV6-ENTRY control, Lane 2: HEK293T cells were transfected with pCMV6-ENTRY SERPINA1 cDNA for 48 hrs using SERPINA1 monoclonal antibody, clone 15H10 (Cat # MAB12493) at 1:500-1:1000 dilution.
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin,serine (or cysteine) proteinase inhibitor, clade A, member 1,serine proteinase inhibitor, clade A, member 1