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HSPG2 monoclonal antibody, clone A7L6

  • Catalog # : MAB12489
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against native human HSPG2.
  • Immunogen:
  • High molecular mass material derived from the Engelbreth-Holm-Swarm (EHS) tumor matrix containing laminin, entactin and HSPG.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunocytochemistry
    Immunohistochemistry (Frozen sections) (1:50)
    Immunoprecipitation (1:100-1:1000)
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemical staining (Frozen sections) of human spleen tissue (A), human kidney tissue (B) and human heart tissue (C) using HSPG2 monoclonal antibody, clone A7L6 (Cat # MAB12489) at 1:50 dilution.
  • Immunocytochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • enlarge
  • Immunocytochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3339
  • Gene Name:
  • HSPG2
  • Gene Alias:
  • PLC,PRCAN,SJA,SJS,SJS1
  • Gene Description:
  • heparan sulfate proteoglycan 2
  • Gene Summary:
  • Heparan sulfate proteoglycan is a major component of basement membranes, where the molecule may be involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. This form of HSPG, known as HSPG2 or perlecan, is encoded by a gene that maps to chromosome 1. The gene for the form of HSPG associated with the cell surface of fibroblasts has been mapped to human chromosome 8 (MIM 142460).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000002765,Schwartz-Jampel syndrome 1 (chondrodystrophic myotonia),endorepellin (domain V region),heparan sulfate proteoglycan of basement membrane,perlecan proteoglycan
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