HSPG2 monoclonal antibody, clone A7L6
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More Files
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Immunohistochemistry (Frozen sections)
Immunohistochemical staining (Frozen sections) of human spleen tissue (A), human kidney tissue (B) and human heart tissue (C) using HSPG2 monoclonal antibody, clone A7L6 (Cat # MAB12489) at 1:50 dilution.
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Specification
Product Description
Rat monoclonal antibody raised against native human HSPG2.
Immunogen
High molecular mass material derived from the Engelbreth-Holm-Swarm (EHS) tumor matrix containing laminin, entactin and HSPG.
Host
Rat
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG2a
Recommend Usage
Immunocytochemistry
Immunohistochemistry (Frozen sections) (1:50)
Immunoprecipitation (1:100-1:1000)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunohistochemical staining (Frozen sections) of human spleen tissue (A), human kidney tissue (B) and human heart tissue (C) using HSPG2 monoclonal antibody, clone A7L6 (Cat # MAB12489) at 1:50 dilution.Immunocytochemistry
Immunoprecipitation
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Gene Info — HSPG2
Entrez GeneID
3339Protein Accession#
P98160Gene Name
HSPG2
Gene Alias
PLC, PRCAN, SJA, SJS, SJS1
Gene Description
heparan sulfate proteoglycan 2
Gene Ontology
HyperlinkGene Summary
Heparan sulfate proteoglycan is a major component of basement membranes, where the molecule may be involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. This form of HSPG, known as HSPG2 or perlecan, is encoded by a gene that maps to chromosome 1. The gene for the form of HSPG associated with the cell surface of fibroblasts has been mapped to human chromosome 8 (MIM 142460).[supplied by OMIM
Other Designations
OTTHUMP00000002765|Schwartz-Jampel syndrome 1 (chondrodystrophic myotonia)|endorepellin (domain V region)|heparan sulfate proteoglycan of basement membrane|perlecan proteoglycan
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Interactome
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Pathway
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Disease
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