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LOX monoclonal antibody, clone 9A11

  • Catalog # : MAB12485
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human LOX.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 22-168 of human LOX.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (1:100)
    Immunofluorescence (1:50-1:100)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (1% BSA, 50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of Lane 1: HEK293T cells were transfected with the pCMV6-ENTRY control, Lane 2: HEK293T cells were transfected with pCMV6-ENTRY LOX cDNA for 48 hrs using LOX monoclonal antibody, clone 9A11 (Cat # MAB12485) at 1:2000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis tissue with LOX monoclonal antibody, clone 9A11 (Cat # MAB12485) under 10 ug/mL working concentration.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of HepG2 cells (A) and COS7 cells (B) using LOX monoclonal antibody, clone 9A11 (Cat # MAB12485) at 1:50-1:100 dilution.
  • Flow Cytometry
  • Flow Cytometry
  • Flow Cyotometry anlaysis of HeLa cells using LOX monoclonal antibody, clone 9A11 (Cat # MAB12485) at 1:100 dilution.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4015
  • Gene Name:
  • LOX
  • Gene Alias:
  • MGC105112
  • Gene Description:
  • lysyl oxidase
  • Gene Summary:
  • The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. [provided by RefSeq
  • Other Designations:
  • protein-lysine 6-oxidase
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