Mouse monoclonal antibody raised against partial recombinant human LOX.
Recombinant protein corresponding to amino acids 22-168 of human LOX.
Protein A/G purification
Flow Cytometry (1:100) Immunofluorescence (1:50-1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:2000) The optimal working dilution should be determined by the end user.
Western blot analysis of Lane 1: HEK293T cells were transfected with the pCMV6-ENTRY control, Lane 2: HEK293T cells were transfected with pCMV6-ENTRY LOX cDNA for 48 hrs using LOX monoclonal antibody, clone 9A11 (Cat # MAB12485) at 1:2000 dilution.
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. [provided by RefSeq