Mouse monoclonal antibody raised against partial synthetic peptide of human GAD2.
A synthetic peptide (conjugated with KLH) corresponding to amino acids 4-22 at the N-terminus of human GAD2.
Protein G purification
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation Radioimmunoassay Western Blot (1:100-1:1000) The optimal working dilution should be determined by the end user.
In PBS (0.09% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq