Western blot analysis of SW480 cell lystae using XPA monoclonal antibody, clone AT37C5 (Cat # MAB12476) at the following dilution factor: Lane 1: 1:500 dilution, Lane 2: 1:1000 dilution, Lane 3: 1:2000 dilution.
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq