Mouse monoclonal antibody raised against full length recombinant human POR.
Recombinant protein corresponding to full length of human POR.
Protein A/G purification
Flow Cytometry (1:100) Immunofluorescence (1:50-1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100) Western Blot (1:2000) The optimal working dilution should be determined by the end user.
Western blot analysis of Lane 1: HEK293T cells were transfected with the pCMV6-ENTRY control, Lane 2: HEK293T cells were transfected with pCMV6-ENTRY POR cDNA for 48 hrs using POR monoclonal antibody, clone 6C4 (Cat # MAB12467) at 1:2000 dilution.
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq