ITGAM monoclonal antibody, clone 4AM216 (PE)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of human peripheral blood granulocytes reacted with ITGAM monoclonal antibody, clone 4AM216 (PE) (Cat # MAB12388).
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Specification
Product Description
Mouse monoclonal antibody raised against human ITGAM.
Immunogen
ITGAM
Host
Mouse
Reactivity
Human
Form
Liquid
Conjugation
PE
Purification
Protein A/G affinity chromatography
Isotype
IgG1
Recommend Usage
Flow cytometry
Immunofluorescence
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Flow Cytometry
Flow cytometric analysis of human peripheral blood granulocytes reacted with ITGAM monoclonal antibody, clone 4AM216 (PE) (Cat # MAB12388). -
Gene Info — ITGAM
Entrez GeneID
3684Gene Name
ITGAM
Gene Alias
CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6
Gene Description
integrin, alpha M (complement component 3 receptor 3 subunit)
Omim ID
120980Gene Ontology
HyperlinkGene Summary
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
antigen CD11b (p170)|complement component receptor 3, alpha|integrin alpha M|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit
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Interactome
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Disease
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