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CHRM2 monoclonal antibody, clone 1424CT461.78.60

  • Catalog # : MAB12363
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human CHRM2.
  • Immunogen:
  • Recombinant protein corresponding to human CHRM2.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (1:25)
    Immunohistochemistry (1:25)
    Immunofluorescence (1:25)
    Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: SH-SY5Y cell line lysates Lane 2: human brain tissue lysates Lane 3: mouse brain tissue lysates reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:500 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human brain section reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of SH-SY5Y cells reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of SH-SY5Y cells (green histogram) and an isotype control of mouse IgG1 (blue histogram) reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1129
  • Gene Name:
  • CHRM2
  • Gene Alias:
  • FLJ43243,HM2,MGC120006,MGC120007
  • Gene Description:
  • cholinergic receptor, muscarinic 2
  • Gene Summary:
  • The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
  • Other Designations:
  • 7TM receptor,cholinergic receptor, muscarinic 2, isoform a,muscarinic M2 receptor,muscarinic acetylcholine receptor M2
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