CHRM2 monoclonal antibody, clone 1424CT461.78.60
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: SH-SY5Y cell line lysates Lane 2: human brain tissue lysates Lane 3: mouse brain tissue lysates reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:500 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain section reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.
Immunofluorescence
Immunofluorescent staining of SH-SY5Y cells reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.
Flow Cytometry
Flow cytometric analysis of SH-SY5Y cells (green histogram) and an isotype control of mouse IgG1 (blue histogram) reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against human CHRM2.
Immunogen
Recombinant protein corresponding to human CHRM2.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (1:25)
Immunohistochemistry (1:25)
Immunofluorescence (1:25)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: SH-SY5Y cell line lysates Lane 2: human brain tissue lysates Lane 3: mouse brain tissue lysates reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain section reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.Immunofluorescence
Immunofluorescent staining of SH-SY5Y cells reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution.Flow Cytometry
Flow cytometric analysis of SH-SY5Y cells (green histogram) and an isotype control of mouse IgG1 (blue histogram) reacted with CHRM2 monoclonal antibody (Cat # MAB12363) at 1:25 dilution. -
Gene Info — CHRM2
Entrez GeneID
1129Gene Name
CHRM2
Gene Alias
FLJ43243, HM2, MGC120006, MGC120007
Gene Description
cholinergic receptor, muscarinic 2
Omim ID
118493Gene Ontology
HyperlinkGene Summary
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
Other Designations
7TM receptor|cholinergic receptor, muscarinic 2, isoform a|muscarinic M2 receptor|muscarinic acetylcholine receptor M2
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Interactome
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Pathway
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Disease
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