VAMP8 monoclonal antibody, clone 1414CT354.12.23.93
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane 1: Hela cell line lysates Lane 2: THP-1 cell line lysates Lane 3: A431 cell line lysates reacted with VAMP8 monoclonal antibody (Cat # MAB12361) at 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain section reacted with VAMP8 monoclonal antibody (Cat # MAB12361) at 1:25 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human VAMP8.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 2~24 at N-terminus region of human VAMP8.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (1:25)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: Hela cell line lysates Lane 2: THP-1 cell line lysates Lane 3: A431 cell line lysates reacted with VAMP8 monoclonal antibody (Cat # MAB12361) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain section reacted with VAMP8 monoclonal antibody (Cat # MAB12361) at 1:25 dilution. -
Gene Info — VAMP8
Entrez GeneID
8673Gene Name
VAMP8
Gene Alias
EDB
Gene Description
vesicle-associated membrane protein 8 (endobrevin)
Omim ID
603177Gene Ontology
HyperlinkGene Summary
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment. It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex. [provided by RefSeq
Other Designations
endobrevin|vesicle-associated membrane protein 8
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Interactome
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Pathway
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Disease
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