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Last updated: 2017/3/26

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VAMP8 monoclonal antibody, clone 1414CT354.12.23.93

  • Catalog # : MAB12361
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human VAMP8.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 2~24 at N-terminus region of human VAMP8.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (1:25)
    Western Blot (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Lane 1: Hela cell line lysates Lane 2: THP-1 cell line lysates Lane 3: A431 cell line lysates reacted with VAMP8 monoclonal antibody (Cat # MAB12361) at 1:1000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human brain section reacted with VAMP8 monoclonal antibody (Cat # MAB12361) at 1:25 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8673
  • Gene Name:
  • VAMP8
  • Gene Alias:
  • EDB
  • Gene Description:
  • vesicle-associated membrane protein 8 (endobrevin)
  • Gene Summary:
  • Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment. It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex. [provided by RefSeq
  • Other Designations:
  • endobrevin,vesicle-associated membrane protein 8
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