ATG3 monoclonal antibody, clone 1377CT239.6.1.12
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Specification
Product Description
Mouse monoclonal antibody raised against human ATG3.
Immunogen
Recombinant protein corresponding to human ATG3.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (1:25)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: THP-1 cell line lysates Lane 2: mouse liver tissue lysates Lane 3: mouse testis tissue lysates reacted with ATG3 monoclonal antibody (Cat # MAB12360) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human kidney section reacted with ATG3 monoclonal antibody (Cat # MAB12360) at 1:25 dilution. -
Gene Info — ATG3
Entrez GeneID
64422Gene Name
ATG3
Gene Alias
APG3, APG3-LIKE, APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96
Gene Description
ATG3 autophagy related 3 homolog (S. cerevisiae)
Omim ID
609606Gene Ontology
HyperlinkGene Summary
Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy (Tanida et al., 2002 [PubMed 11825910]).[supplied by OMIM
Other Designations
2610016C12Rik|APG3 autophagy 3-like|Apg3p|autophagy Apg3p/Aut1p-like
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Interactome
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Pathway
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Disease
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