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PPARA monoclonal antibody, clone 1331CT894.186.143

  • Catalog # : MAB12349
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human PPARA.
  • Immunogen:
  • Recombinant protein corresponding to human PPARA.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (1:25)
    Immunohistochemistry (1:25)
    Immunofluorescence (1:25)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Lane 1: Hela cell line lysates Lane 2: Jurkat cell line lysates Lane 3: mouse NIH/3T3 cell line lysates reacted with PPARA monoclonal antibody (Cat # MAB12349) at 1:1000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human skeletal muscle section reacted with PPARA monoclonal antibody (Cat # MAB12349) at 1:25 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of Hela cells reacted with PPARA monoclonal antibody (Cat # MAB12349) at 1:25 dilution.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of Hela cells (green histogram) and an isotype control of mouse IgG1 (blue histogram) reacted with PPARA monoclonal antibody (Cat # MAB12349) at 1:25 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5465
  • Gene Name:
  • PPARA
  • Gene Alias:
  • MGC2237,MGC2452,NR1C1,PPAR,hPPAR
  • Gene Description:
  • peroxisome proliferator-activated receptor alpha
  • Gene Summary:
  • Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028713,OTTHUMP00000042872,peroxisome proliferative activated receptor, alpha,peroxisome proliferator activated receptor alpha
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