FLT4 monoclonal antibody, clone 818CT12.1.1
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane 1: 293 cell line lysates Lane 2: A549 cell line lysates reacted with FLT4 monoclonal antibody (Cat # MAB12341) at 1:2000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human testis section reacted with FLT4 monoclonal antibody (Cat # MAB12341) at 1:25 dilution.
Flow Cytometry
Flow cytometric analysis of HUVEC cells (green histogram) and an isotype control of mouse IgG2a (blue histogram) reacted with FLT4 monoclonal antibody (Cat # MAB12341) at 1:25 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against human FLT4.
Immunogen
Recombinant His fusion protein corresponding to human FLT4.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG2a
Recommend Usage
Flow Cytometry (1:25)
Immunohistochemistry (1:25)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: 293 cell line lysates Lane 2: A549 cell line lysates reacted with FLT4 monoclonal antibody (Cat # MAB12341) at 1:2000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human testis section reacted with FLT4 monoclonal antibody (Cat # MAB12341) at 1:25 dilution.Flow Cytometry
Flow cytometric analysis of HUVEC cells (green histogram) and an isotype control of mouse IgG2a (blue histogram) reacted with FLT4 monoclonal antibody (Cat # MAB12341) at 1:25 dilution. -
Gene Info — FLT4
Entrez GeneID
2324Gene Name
FLT4
Gene Alias
FLT41, LMPH1A, PCL, VEGFR3
Gene Description
fms-related tyrosine kinase 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq
Other Designations
soluble VEGFR3 variant 1|soluble VEGFR3 variant 2|soluble VEGFR3 variant 3|vascular endothelial growth factor receptor 3
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Interactome
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Pathway
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Disease
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Publication Reference
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A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis.
Zhang JX, He WL, Feng ZH, Chen DL, Gao Y, He Y, Qin K, Zheng ZS, Chen C, Weng HW, Yun M, Ye S, Xu RH, Xie D.
Journal of Experimental & Clinical Cancer Research 2019 Apr; 38(1):164.
Application：WB-Tr, Human, MKN-45 cells.
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A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis.
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