UCHL1 monoclonal antibody, clone 696CT2.1.4
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane 1: 293T cell line lysates Lane 2: NCI-H1299 cell line lysates Lane 3: rat PC-12 cell line lysates reacted with UCHL1 monoclonal antibody (Cat # MAB12336) at 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain section reacted with UCHL1 monoclonal antibody (Cat # MAB12336) at 1:25 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human UCHL1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 185-214 of human UCHL1.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (1:25)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: 293T cell line lysates Lane 2: NCI-H1299 cell line lysates Lane 3: rat PC-12 cell line lysates reacted with UCHL1 monoclonal antibody (Cat # MAB12336) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human brain section reacted with UCHL1 monoclonal antibody (Cat # MAB12336) at 1:25 dilution. -
Gene Info — UCHL1
Entrez GeneID
7345Gene Name
UCHL1
Gene Alias
PARK5, PGP9.5, Uch-L1
Gene Description
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease
Other Designations
ubiquitin C-terminal esterase L1|ubiquitin carboxyl-terminal esterase L1|ubiquitin thiolesterase L1
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Interactome
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Disease
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