Western blot analysis of Lane 1: MCF-7 cell line lysates Lane 2: A431 cell line lysates Lane 3: Hela cell line lysates Lane 4: HepG2 cell line lysates Lane 5: mouse NIH/3T3 cell line lysates Lane 6: mouse stomach tissue lysates Lane 7: liver tissue lysates reacted with ENO1 monoclonal antibody (Cat # MAB12329) at 1:1000 dilution.
This gene encodes one of three enolase isoenzymes found in mammals; it encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. A pseudogene has been identified that is located on the other arm of the same chromosome. [provided by RefSeq
2-phospho-D-glycerate hydro-lyase,MYC promoter-binding protein 1,OTTHUMP00000001706,alpha enolase like 1,enolase 1,non-neural enolase,phosphopyruvate hydratase,tau-crystallin