SOD2 monoclonal antibody, clone 37CT127.5.11.6
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysates Lane 2: human brain lysates Lane 3: human heart lysates Lane 4: human liver lysates reacted with SOD2 monoclonal antibody (Cat # MAB12323) at 1:2000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOD2 monoclonal antibody (Cat # MAB12323) at 1:10-1:50 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human SOD2.
Immunogen
Recombinant His fusion protein corresponding to human SOD2.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (1:10-1:50)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysates Lane 2: human brain lysates Lane 3: human heart lysates Lane 4: human liver lysates reacted with SOD2 monoclonal antibody (Cat # MAB12323) at 1:2000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOD2 monoclonal antibody (Cat # MAB12323) at 1:10-1:50 dilution. -
Gene Info — SOD2
Entrez GeneID
6648Gene Name
SOD2
Gene Alias
IPO-B, MNSOD, Mn-SOD
Gene Description
superoxide dismutase 2, mitochondrial
Omim ID
147460Gene Ontology
HyperlinkGene Summary
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
Mn superoxide dismutase|OTTHUMP00000017530|OTTHUMP00000017531|indophenoloxidase B|manganese superoxide dismutase|manganese-containing superoxide dismutase|mangano-superoxide dismutase
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Interactome
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Disease
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