RET monoclonal antibody, clone 188CT11.2.3
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of A549 cell line lysates reacted with RET monoclonal antibody (Cat # MAB12308) at 1:500-1:16000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human brain tissue reacted with RET monoclonal antibody (Cat # MAB12308) at 1:50-1:100 dilution.
Immunofluorescence
Immunofluorescent staining of MDA-MB231 cell reacted with RET monoclonal antibody (Cat # MAB12308) at 1:10-1:50 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against human RET.
Immunogen
Recombinant His fusion protein corresponding to human RET.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgM, kappa
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:10-1:50)
Western Blot (1:500-1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of A549 cell line lysates reacted with RET monoclonal antibody (Cat # MAB12308) at 1:500-1:16000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human brain tissue reacted with RET monoclonal antibody (Cat # MAB12308) at 1:50-1:100 dilution.Immunofluorescence
Immunofluorescent staining of MDA-MB231 cell reacted with RET monoclonal antibody (Cat # MAB12308) at 1:10-1:50 dilution. -
Gene Info — RET
Entrez GeneID
5979Gene Name
RET
Gene Alias
CDHF12, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Gene Description
ret proto-oncogene
Gene Ontology
HyperlinkGene Summary
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq
Other Designations
RET transforming sequence|cadherin family member 12|hydroxyaryl-protein kinase|oncogene RET|receptor tyrosine kinase|ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
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Interactome
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Pathway
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Disease
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