ALDH6A1 monoclonal antibody, clone 147CT8.3.4
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Specification
Product Description
Mouse monoclonal antibody raised against human ALDH6A1.
Immunogen
Recombinant protein corresponding to human ALDH6A1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (1:25)
Immunofluorescence (1:25)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: MCF-7 cell line lysates Lane 2: T47D cell line lysates reacted with ALDH6A1 monoclonal a tibody (Cat # MAB12296) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human colon section reacted with ALDH6A1 monoclonal antibody (Cat # MAB12296) at 1:25 dilution.Immunofluorescence
Immunofluorescent staining of MCF-7 cells reacted with ALDH6A1 monoclonal antibody (Cat # MAB12296) at 1:25 dilution. -
Gene Info — ALDH6A1
Entrez GeneID
4329Gene Name
ALDH6A1
Gene Alias
MGC40271, MMSADHA, MMSDH
Gene Description
aldehyde dehydrogenase 6 family, member A1
Omim ID
603178Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq
Other Designations
aldehyde dehydrogenase 6A1|mitochondrial acylating methylmalonate-semialdehyde dehydrogenase
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Interactome
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Disease
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