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ALDH2 monoclonal antibody, clone 138CT22.3.8

  • Catalog # : MAB12292
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human ALDH2.
  • Immunogen:
  • Recombinant protein corresponding to human ALDH2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (1:10-1:50)
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:10-1:50)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Lane 1: NCI-H292 whole cell lysates Lane 2: A549 whole cell lysates Lane 3: HepG2 whole cell lysates reacted with ALDH2 monoclonal antibody (Cat # MAB12292) at 1:1000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of formalin-fixed and paraffin-embedded human brain tissue reacted with ALDH2 monoclonal antibody (Cat # MAB12292) at 1:50-1:100 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of HepG2 cell reacted with ALDH2 monoclonal antibody (Cat # MAB12292) at 1:10-1:50 dilution.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HepG2 cells (right histogram) and a negative control cell (left histogram) reacted with ALDH2 monoclonal antibody (Cat # MAB12292) at 1:10-1:50 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 217
  • Gene Name:
  • ALDH2
  • Gene Alias:
  • ALDH-E2,ALDHI,ALDM,MGC1806
  • Gene Description:
  • aldehyde dehydrogenase 2 family (mitochondrial)
  • Gene Summary:
  • This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq
  • Other Designations:
  • ALDH class 2,acetaldehyde dehydrogenase 2,liver mitochondrial ALDH,mitochondrial aldehyde dehydrogenase 2,nucleus-encoded mitochondrial aldehyde dehydrogenase 2
  • Related Disease
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