ROR2 monoclonal antibody, clone 6F2D10
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ROR2.
Immunogen
Recombinant protein corresponding to amino acids 59-155 of human ROR2.
Host
Mouse
Theoretical MW (kDa)
104.8
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control [HEK293 cell lysate]; Lane 2: Over-expression lysate [ROR2 (AA: 59-155)-hIgGFc transfected HEK293 cells] with ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:500-1:2000 dilution.Western Blot (Recombinant protein)
Western blot analysis of human ROR2 (AA: 59-155) recombinant protein (Expected MW is 36.8 kDa) with ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:500-1:2000 dilution.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:10000 dilution.Flow Cytometry
Flow cytometric analysis of Hela cells with ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:200-1:400 dilution (Green) and negative control (Red). -
Gene Info — ROR2
Entrez GeneID
4920Gene Name
ROR2
Gene Alias
BDB, BDB1, MGC163394, NTRKR2
Gene Description
receptor tyrosine kinase-like orphan receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq
Other Designations
OTTHUMP00000021634|OTTHUMP00000063680|neurotrophic tyrosine kinase receptor-related 2|tyrosine-protein kinase transmembrane receptor ROR2
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Interactome
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Disease
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