Western blot analysis of Lane 1: Negative control [HEK293 cell lysate]; Lane 2: Over-expression lysate [ROR2 (AA: 59-155)-hIgGFc transfected HEK293 cells] with ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:500-1:2000 dilution.
Western Blot (Recombinant protein)
Western blot analysis of human ROR2 (AA: 59-155) recombinant protein (Expected MW is 36.8 kDa) with ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:500-1:2000 dilution.
ELISA analysis of ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:10000 dilution.
Flow Cytometry analysis of Hela cells with ROR2 monoclonal antibody, clone 6F2D10 (Cat# MAB12258) at 1:200-1:400 dilution (Green) and negative control (Red).
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq