Western blot analysis of Lane 1: Negative control [HEK293 cell lysate]; Lane 2: Over-expression lysate [PLA2G12A (AA: 21-189)-hIgGFc transfected HEK293 cells] with PLA2G12A monoclonal antibody, clone 3H2C11 (Cat# MAB12250) at 1:500-1:2000 dilution.
Western Blot (Recombinant protein)
Western blot analysis of human PLA2G12A (AA: 21-189) recombinant protein (Expected MW is 44.5 kDa) with PLA2G12A monoclonal antibody, clone 3H2C11 (Cat# MAB12250) at 1:500-1:2000 dilution.
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM
group XII secreted phospholipase A2,group XIIA secreted phospholipase A2