ENG monoclonal antibody, clone SN6 (PE)
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Specification
Product Description
Mouse monoclonal antibody raised against ENG.
Immunogen
ENG
Host
Mouse
Reactivity
Human
Form
Liquid
Conjugation
PE
Purification
Affinity Chromatography
Isotype
IgG1
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (0.09% Sodium azide, may contain carrier protein/stabilizer).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of viable U937 cells using ENG monoclonal antibody, clone SN6 (PE) (Cat # MAB12233) compared to a relevant isotype control in blue. -
Gene Info — ENG
Entrez GeneID
2022Gene Name
ENG
Gene Alias
CD105, END, FLJ41744, HHT1, ORW, ORW1
Gene Description
endoglin
Gene Ontology
HyperlinkGene Summary
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD105 antigen|OTTHUMP00000022221|Osler-Rendu-Weber syndrome 1
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Interactome
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Disease
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