ITGAM monoclonal antibody, clone 53-6.7 (FITC)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes using ITGAM monoclonal antibody, clone monoclonal antibody, clone 53-6.7 (FITC) (Cat # MAB12218) compared to a relevant isotype control in red.
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Specification
Product Description
Mouse monoclonal antibody raised against ITGAX.
Immunogen
ITGAM
Host
Mouse
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Affinity Chromatography
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (0.09% Sodium azide, may contain carrier protein/stabilizer).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes using ITGAM monoclonal antibody, clone monoclonal antibody, clone 53-6.7 (FITC) (Cat # MAB12218) compared to a relevant isotype control in red. -
Gene Info — ITGAM
Entrez GeneID
3684Gene Name
ITGAM
Gene Alias
CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6
Gene Description
integrin, alpha M (complement component 3 receptor 3 subunit)
Omim ID
120980Gene Ontology
HyperlinkGene Summary
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
antigen CD11b (p170)|complement component receptor 3, alpha|integrin alpha M|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit
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Interactome
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Pathway
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Disease
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