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Last updated: 2017/9/24

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C19orf2 monoclonal antibody, clone SP215

  • Catalog # : MAB12180
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of C19orf2.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus region of human C19orf2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 57
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:100)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-Fixed Paraffin-Embedded Sections) staining of human ovarian adenocarcinoma with C19orf2 monoclonal antibody, clone SP215 (Cat # MAB12180).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of 293 cells with C19orf2 monoclonal antibody, clone SP215 (Cat # MAB12180).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8725
  • Gene Name:
  • C19orf2
  • Gene Alias:
  • FLJ10575,NNX3,RMP,URI
  • Gene Description:
  • chromosome 19 open reading frame 2
  • Gene Summary:
  • The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • RNA polymerase II, subunit 5-mediating protein,RPB5-mediating protein,unconventional prefoldin RPB5 interactor
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