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CDH17 monoclonal antibody, clone SP183

  • Catalog # : MAB12160
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CDH17.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus region of human CDH17.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 120
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon (A) and human colon adenocarcinoma (B) with CDH17 monoclonal antibody, clone SP183 (Cat# MAB12160) at 1:100 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1015
  • Gene Name:
  • CDH17
  • Gene Alias:
  • CDH16,FLJ26931,HPT-1,HPT1,MGC138218,MGC142024
  • Gene Description:
  • cadherin 17, LI cadherin (liver-intestine)
  • Gene Summary:
  • This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • HPT-1 cadherin,LI cadherin,cadherin 17,cadherin-16,human intestinal peptide-associated transporter HPT-1,human peptide transporter 1,liver-intestine cadherin
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