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Cd44 variant isoform 10-exon 16 (v10-e16) monoclonal antibody, clone RM1

  • Catalog # : MAB12150
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against mouse Cd44 variant isoform 10-exon 16 (v10-e16).
  • Immunogen:
  • Mouse Cd44 variant isoform 8-10 transfected cell.
  • Host:
  • Rat
  • Reactivity:
  • Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow cytomerty (1-10 ug/mL)
    Cancer stem cell enrichment
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS
  • Storage Instruction:
  • Store at 2-8°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Cancer Stem Cell Enrichment
    Cancer Stem Cells (CSCs) have been identified as a subset of distinct population in many tumors and can drive cancer relapse and metastasis with their abilities to self-renew and differentiate into various types of cancer cells. Development of therapies specifically and effectively targeting CSCs thus is necessary to improve the survival and quality of life for cancer patients, especially for patients with metastatic diseases.
    Clone RM1 can be used for enrichment of CSCs with a cell sorter, and further be applied for studying mechanisms by which CSCs cause cancer relapse and metastasis to develop new drugs against CSCs.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometry analysis of mouse breast cancer cell line 4T1 with Cd44 (v10-e16) monoclonal antibody, clone RM1 (Cat # MAB12150) at 3 ug/mL concentration and PE-labeled anti Rat IgG antibody.
  • Flow Cytometry
  • Flow Cytometry enlargeenlarge this image
  • CSC enrichment from mouse cancer cell line using anti-CD44v10-e16 monoclonal antibody, clone RM1 (Cat # MAB12150) at 3 ug/mL.
  • Application Image
  • Gene Information
  • Gene Name:
  • Cd44
  • Gene Alias:
  • AU023126,AW121933,AW146109,HERMES,Ly-24,Pgp-1
  • Gene Description:
  • CD44 antigen
  • Other Designations:
  • OTTMUSP00000015733,OTTMUSP00000015734,OTTMUSP00000015735
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