UCHL1 monoclonal antibody, clone SPM574
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Specification
Product Description
Mouse monoclonal antibody raised against native UCHL1.
Immunogen
Native purified human UCHL1 from brain.
Host
Mouse
Theoretical MW (kDa)
20-30
Reactivity
Bovine, Human, Mouse, Pig, Rat
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (0.5-1 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of UCHL1 in
Lane 1: Human brain lysate
Lane 2: Mouse brain lysate
Lane 3: Rat brain lysate
with UCHL1 monoclonal antibody, clone SPM574 (Cat# MAB12063).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain with UCHL1 monoclonal antibody, clone SPM574 (Cat# MAB12063). -
Gene Info — UCHL1
Entrez GeneID
7345Gene Name
UCHL1
Gene Alias
PARK5, PGP9.5, Uch-L1
Gene Description
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease
Other Designations
ubiquitin C-terminal esterase L1|ubiquitin carboxyl-terminal esterase L1|ubiquitin thiolesterase L1
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Interactome
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Disease
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