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Last updated: 2017/5/28

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TYR monoclonal antibody, clone SPM360

  • Catalog # : MAB12061
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant TYR.
  • Immunogen:
  • Recombinant protein corresponding to human tyrosinase.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 70-80
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Immunohistochemistry (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human melanoma tissue with TYR monoclonal antibody, clone SPM360 (Cat# MAB12061).
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 7299
  • Gene Name:
  • TYR
  • Gene Alias:
  • OCA1A,OCAIA,SHEP3
  • Gene Description:
  • tyrosinase (oculocutaneous albinism IA)
  • Gene Summary:
  • The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
  • Other Designations:
  • tyrosinase
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