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SUMO2/SUMO3 monoclonal antibody, clone SPM572

  • Catalog # : MAB12055
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against SUMO2/SUMO3.
  • Immunogen:
  • Recombinant protein corresponding to human SUMO2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 11-13
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with SUMO2/SUMO3 monoclonal antibody, clone SPM572 (Cat# MAB12055).
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 6613
  • Gene Name:
  • SUMO2
  • Gene Alias:
  • HSMT3,MGC117191,SMT3B,SMT3H2
  • Gene Description:
  • SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • SMT3 suppressor of mif two 3 homolog 2,sentrin 2,small ubiquitin-like modifier 2, isoform a
  • Gene Information
  • Entrez GeneID:
  • 6612
  • Gene Name:
  • SUMO3
  • Gene Alias:
  • SMT3A,SMT3H1,SUMO-3
  • Gene Description:
  • SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
  • Gene Summary:
  • SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000115275,SMT3 suppressor of mif two 3 homolog 1,small ubiquitin-like modifier protein 3
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