Products

Western Blot

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Entrez GeneID

Gene Name

SUMO3

Gene Alias

SMT3A, SMT3H1, SUMO-3

Gene Description

SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)

Omim ID

Gene Ontology

Gene Summary

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM

Other Designations

OTTHUMP00000115275|SMT3 suppressor of mif two 3 homolog 1|small ubiquitin-like modifier protein 3

Entrez GeneID

Gene Name

SUMO2

Gene Alias

HSMT3, MGC117191, SMT3B, SMT3H2

Gene Description

SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

Omim ID

Gene Ontology

Gene Summary

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Other Designations

SMT3 suppressor of mif two 3 homolog 2|sentrin 2|small ubiquitin-like modifier 2, isoform a