CHGA monoclonal antibody, clone SPM585
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Specifications
Product Description
Mouse monoclonal antibody raised against CHGA.
Immunogen
Human pheochromocytoma.
Host
Mouse
Theoretical MW (kDa)
68-75
Reactivity
Human
Specificity
Does not react with mouse and rat.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (0.5-1 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung carcinoma with CHGA monoclonal antibody, clone SPM585 (Cat # MAB12042). -
Gene Info — CHGA
Entrez GeneID
1113Gene Name
CHGA
Gene Alias
CGA
Gene Description
chromogranin A (parathyroid secretory protein 1)
Omim ID
118910Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq
Other Designations
betagranin (N-terminal fragment of chromogranin A)|chromogranin A|parathyroid secretory protein 1
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