Mouse monoclonal antibody raised against recombinant of SLC5A5.
Immunogen:
Recombinant mannose fusion protien corresponding to amino acids 468-643 of human SLC5A5.
Host:
Mouse
Reactivity:
Human, Mouse, Rat
Specificity:
Mapped to amino acids 625-643 of hNIS. Apparent mol. wt of 97 kD, non-glycosylated version at 68 kD. Other minor bands associated with hNIS at 160 kDa, and degradation products at ~30 kDa, and ~15kDa.
Form:
Liquid
Purification:
Protein G purification
Isotype:
IgG1, kappa
Recommend Usage:
Immunofluorescence Immunohistochemistry Western blot (1:1000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH 7.4 (50% glycerol)
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1