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C4A monoclonal antibody, clone TDM16

  • Catalog # : MAB11491
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against C4A.
  • Immunogen:
  • Human C4A.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunofluorescence (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • 10mM PBS, 0.05%BSA, and 0.05% Azide
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Application Image
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 720
  • Gene Name:
  • C4A
  • Gene Alias:
  • C4,C4A2,C4A3,C4A4,C4A6,C4S,CO4,CPAMD2,MGC164979,RG
  • Gene Description:
  • complement component 4A (Rodgers blood group)
  • Gene Summary:
  • This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq
  • Other Designations:
  • C4A anaphylatoxin,OTTHUMP00000029266,Rodgers form of C4,acidic C4,complement component 4A
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