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VIM monoclonal antibody, clone LN6

  • Catalog # : MAB11483
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  • Specification
  • Product Description:
  • mouse monoclonal antibody raised against VIM.
  • Immunogen:
  • Human thymic nuclear extract.
  • Host:
  • Mouse
  • Reactivity:
  • Bovine, Cat, Human, Mouse, Pig, Rabbit, Rat, Sheep
  • Form:
  • liquid
  • Isotype:
  • IgM
  • Recommend Usage:
  • Immunofluorescence (1:50-1:100)
    Immunohistochemistry (1:100-1:200 for 30 min at RT)
    Western Blot (1:400-1:800)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Culture supernatant with 0.05% Azide
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human melanoma with VIM monoclonal antibody, clone LN6 (Cat # MAB11483) at 1:100-1:200 dilution for 30 min at RT.
  • Immunofluorescence
  • Application Image
  • Western Blot
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 7431
  • Gene Name:
  • VIM
  • Gene Alias:
  • FLJ36605
  • Gene Description:
  • vimentin
  • Gene Summary:
  • This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract
  • Other Designations:
  • OTTHUMP00000019224
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