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MET monoclonal antibody, clone 4AT259 

  • Catalog # : MAB1146
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant MET.
  • Immunogen:
  • Recombinant protein corresponding to catalytic region of human MET.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:100-500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 2.
  • Further evidence for the role of MET in autism susceptibility.
    Thanseem I, Nakamura K, Miyachi T, Toyota T, Yamada S, Tsujii M, Tsuchiya KJ, Anitha A, Iwayama Y, Yamada K, Hattori E, Matsuzaki H, Matsumoto K, Iwata Y, Suzuki K, Suda S, Kawai M, Sugihara G, Takebayashi K, Takei N, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N.Neurosci Res. 2010 Oct;68(2):137-41. Epub 2010 Jul 6.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Detection of endogenous MET in HepG2 cell line. 10 ug/lane of HepG2 cell lysate was used to examine the expression of human MET. Lanes 1-5 represent MET monoclonal antibody, clone 4AT259 (Cat # MAB1146). Lane 6 represents auto-phosohorylated-MET in HepG2 cell line detected by anti-phospho-MET monaclonal antibody (Cat # MAB0115).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4233
  • Gene Name:
  • MET
  • Gene Alias:
  • AUTS9,HGFR,RCCP2,c-Met
  • Gene Description:
  • met proto-oncogene (hepatocyte growth factor receptor)
  • Gene Summary:
  • The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • HGF receptor,OTTHUMP00000069168,SF receptor,met proto-oncogene,met proto-oncogene tyrosine kinase,oncogene MET,scatter factor receptor
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