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L1CAM monoclonal antibody, clone UJ127

  • Catalog # : MAB11365
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against L1CAM.
  • Immunogen:
  • Homogenous suspension of 16 week human fetal brain.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G affinity chromatography
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Frozen sections) (1-2 ug/mL for 30 min at RT)
    Immunoprecipitation (1-2 ug/500 ug protein)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3897
  • Gene Name:
  • L1CAM
  • Gene Alias:
  • CAML1,CD171,HSAS,HSAS1,MASA,MIC5,N-CAML1,S10,SPG1
  • Gene Description:
  • L1 cell adhesion molecule
  • Gene Summary:
  • The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025992,antigen identified by monoclonal antibody R1,neural cell adhesion molecule L1
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