L1CAM monoclonal antibody, clone UJ127
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Specification
Product Description
Mouse monoclonal antibody raised against L1CAM.
Immunogen
Homogenous suspension of 16 week human fetal brain.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G affinity chromatography
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Frozen sections) (1-2 ug/mL for 30 min at RT)
Immunoprecipitation (1-2 ug/500 ug protein)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunofluorescence
Immunoprecipitation
Flow Cytometry
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Gene Info — L1CAM
Entrez GeneID
3897Gene Name
L1CAM
Gene Alias
CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1
Gene Description
L1 cell adhesion molecule
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq
Other Designations
OTTHUMP00000025992|antigen identified by monoclonal antibody R1|neural cell adhesion molecule L1
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Interactome
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Pathway
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Disease
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