Homogenous suspension of 16 week human fetal brain.
Protein A/G affinity chromatography
Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Frozen sections) (1-2 ug/mL for 30 min at RT) Immunoprecipitation (1-2 ug/500 ug protein) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide)
Store at 4°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq
OTTHUMP00000025992,antigen identified by monoclonal antibody R1,neural cell adhesion molecule L1