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KRT8 monoclonal antibody, clone H1

  • Catalog # : MAB11343
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against KRT8.
  • Immunogen:
  • Cytoskeleton preparation containing cytokeratin 8.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Rat, Zebra fish
  • Form:
  • Liquid
  • Purification:
  • Protein A/G affinity chromatography
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (1-2 ug/mL for 30 min at RT)
    Immunoprecipitation (1-2 ug/500 ug protein)
    Western Blot (0.25-0.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human colon with KRT8 monoclonal antibody, clone H1 (Cat # MAB11343) at 1-2 ug/mL, for 30 min at RT.
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3856
  • Gene Name:
  • KRT8
  • Gene Alias:
  • CARD2,CK8,CYK8,K2C8,K8,KO
  • Gene Description:
  • keratin 8
  • Gene Summary:
  • This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
  • Other Designations:
  • cytokeratin 8,keratin, type II cytoskeletal 8
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