PGR monoclonal antibody, clone PR501
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant PGR.
Immunogen
Recombinant human Progesterone Receptor protein
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Western Blot (0.5-1.0ug/ml for 2 hours at Room Temp)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS, pH 7.4 (0.05% BSA and 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) analysis of normal human breast (left) and invasive ductal carcinoma (right) with PGR monoclonal antibody, clone PR500 (Cat # MAB11317) at 1:500 using peroxidase-conjugate and DAB chromogen. -
Gene Info — PGR
Entrez GeneID
5241Gene Name
PGR
Gene Alias
NR3C3, PR
Gene Description
progesterone receptor
Omim ID
607311Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
Other Designations
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Interactome
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Disease
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