MAGEA1 monoclonal antibody, clone MA454
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Specification
Product Description
Mouse monoclonal antibody raised against MAGEA1.
Immunogen
A recombinant protein fragment specific to MAGE-1.
Host
Mouse
Theoretical MW (kDa)
42-46
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) analysis of human testis with MAGEA1 monoclonal antibody, clone MA454 (Cat # MAB11321) at 1:200 using peroxidase-conjugate and DAB chromogen.Immunofluorescence
Flow Cytometry
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Gene Info — MAGEA1
Entrez GeneID
4100Gene Name
MAGEA1
Gene Alias
MAGE1, MGC9326
Gene Description
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
Omim ID
300016Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq
Other Designations
OTTHUMP00000025911|melanoma antigen MAGE-1|melanoma antigen family A 1|melanoma antigen family A, 1|melanoma-associated antigen 1|melanoma-associated antigen MZ2-E
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Interactome
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Publication Reference
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The expression of the cancer testis antigen MAGE A4: A favorable prognostic biomarker in salivary gland carcinomas related to low tumor grading.
Vital D, Ikenberg K, Moch H, Roessle M, Huber GF.
Laryngoscope Investigative Otolaryngology 2018 Apr; 3(3):182.
Application:IHC-P, Human, Human salivary gland carcinomas.
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The expression of the cancer testis antigen MAGE A4: A favorable prognostic biomarker in salivary gland carcinomas related to low tumor grading.
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