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MAP4K4 monoclonal antibody, clone SP177

  • Catalog # : MAB11219
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of MAP4K4.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus region of human MAP4K4.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 142
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-Fixed Paraffin-Embedded Sections) staining of human prostate adenocarcinoma with MAP4K4 monoclonal antibody, clone SP177 (Cat # MAB11219).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 9448
  • Gene Name:
  • MAP4K4
  • Gene Alias:
  • FLH21957,FLJ10410,FLJ20373,FLJ90111,HGK,KIAA0687,NIK
  • Gene Description:
  • mitogen-activated protein kinase kinase kinase kinase 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • HPK/GCK-like kinase,hepatocyte progenitor kinase-like/germinal center kinase-like kinase
  • Gene Pathway
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