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MAFK monoclonal antibody, clone AT2F7

  • Catalog # : MAB11212
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant MAFK.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-156 of human MAFK.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.
  • Storage Instruction:
  • Store at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Jurkat cell lysate (30 ug) by using MAFK monoclonal antibody, clone AT2F7 (Cat # MAB11212) (1:1000).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7975
  • Gene Name:
  • MAFK
  • Gene Alias:
  • FLJ32205,MGC71717,NFE2U,P18
  • Gene Description:
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
  • Gene Summary:
  • The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM
  • Other Designations:
  • basic-leucine zipper transcription factor MafK,erythroid transcription factor NF-E2 p18 subunit,nuclear factor erythroid-2, ubiquitous (p18),v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K,v-maf musculoaponeurotic fibrosarcoma oncog
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