TP53I3 monoclonal antibody, clone AT1C9

Catalog # MAB11193

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Size:100 uL
Price: USD $ 329.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of A-549 cell lysate (40 ug) by using TP53I3 monoclonal antibody, clone AT1C9 (Cat # MAB11193) (1:3000).

Immunofluorescence
Application

Immunofluorescence

Immunofluorescence analysis of TP53I3 in A-549 cells. The cell was stained with TP53I3 monoclonal antibody, clone AT1C9 (Cat # MAB11193) (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

  • Specification

    Product Description

    Mouse monoclonal antibody raised against partial recombinant TP53I3.

    Immunogen

    Recombinant protein corresponding to amino acids 1-332 of human TP53I3.

    Host

    Mouse

    Reactivity

    Human

    Form

    Liquid

    Purification

    Protein G purification

    Concentration

    1 mg/mL

    Isotype

    IgG2a, kappa

    Recommend Usage

    ELISA
    Immunocytochemistry
    Immunofluorescence
    Western Blot
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4 (10% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of A-549 cell lysate (40 ug) by using TP53I3 monoclonal antibody, clone AT1C9 (Cat # MAB11193) (1:3000).

    Immunocytochemistry

    Immunofluorescence

    Immunofluorescence analysis of TP53I3 in A-549 cells. The cell was stained with TP53I3 monoclonal antibody, clone AT1C9 (Cat # MAB11193) (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

    Enzyme-linked Immunoabsorbent Assay

  • Gene Info — TP53I3

    Entrez GeneID

    9540

    Protein Accession#

    NP_671713

    Gene Name

    TP53I3

    Gene Alias

    PIG3

    Gene Description

    tumor protein p53 inducible protein 3

    Omim ID

    605171

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000116037|p53-induced gene 3 protein|quinone oxidoreductase homolog

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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