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TP53I3 monoclonal antibody, clone AT1C9

  • Catalog # : MAB11193
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TP53I3.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-332 of human TP53I3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Western Blot (1:3000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Phosphate-Buffered Saline (pH 7.4) with 0.09% sodium azide.
  • Storage Instruction:
  • Store at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of A-549 cell lysate (40 ug) by using TP53I3 monoclonal antibody, clone AT1C9 (Cat # MAB11193) (1:3000).
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9540
  • Gene Name:
  • TP53I3
  • Gene Alias:
  • PIG3
  • Gene Description:
  • tumor protein p53 inducible protein 3
  • Gene Summary:
  • The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000116037,p53-induced gene 3 protein,quinone oxidoreductase homolog
  • Gene Pathway
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