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KRT8/KRT18 monoclonal antibody, clone CK8+18 207 (FITC)

  • Catalog # : MAB11168
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against KRT8/KRT18.
  • Immunogen:
  • Purified human KRT8/KRT18.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 52.5, 45
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • FITC
  • Concentration:
  • 0.2 mg/mL
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunocytochemistry (1:50-1:100)
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (Circulating Tumor Cell) (1:20)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (1% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence (Circulating Tumor Cell)
  • Immunofluorescence (Circulating Tumor Cell)
  • MCF-7 cells were stained with KRT8/KRT18-FITC labeled monoclonal antibody (Green) and PTPRC-PE labeled monoclonal antibody (Orange). The cell nucleus were counterstained with DAPI (Blue).
  • Application Image
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence (Circulating Tumor Cell)
  • Immunofluorescence (Circulating Tumor Cell)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3856
  • Gene Name:
  • KRT8
  • Gene Alias:
  • CARD2,CK8,CYK8,K2C8,K8,KO
  • Gene Description:
  • keratin 8
  • Gene Summary:
  • This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
  • Other Designations:
  • cytokeratin 8,keratin, type II cytoskeletal 8
  • Gene Information
  • Entrez GeneID:
  • 3875
  • Gene Name:
  • KRT18
  • Gene Alias:
  • CYK18,K18
  • Gene Description:
  • keratin 18
  • Gene Summary:
  • KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cell proliferation-inducing protein 46,cytokeratin 18
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