Western blot analysis of RAB2A monoclonal antibody (Cat # MAB11163) at 1:1000 dilution. Lane 1: HepG2 whole cell lysate 40 ug/lane. Lane 2: Ramos whole cell lysate 40 ug/lane. Lane 3: K-562 whole cell lysate 40 ug/lane. Lane 4: HeLa whole cell lysate 40 ug/lane. Predicted band size: 24 KDa. Observed band size: 24 KDa.
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rabs are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking. The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding proteins involved in the regulation of secretion.[supplied by OMIM
RAB2, member RAS oncogene family,small GTP binding protein RAB2A