Western blot analysis of PPP2CA monoclonal antibody (Cat # MAB11160) at 1:1000 dilution. Lane 1: CEM whole cell lysate 40 ug/lane. Lane 2: K-562 whole cell lysate 40 ug/lane. Lane 3: MCF-7 whole cell lysate 40 ug/lane. Predicted band size: 35 KDa. Observed band size: 35 KDa.
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq